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PepMix™ EBV (LMP2)

PepMix™ EBV (LMP2)

PepMix™ EBV (LMP2)
  
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Delivery in 2-5 days
397,00 €
397,00 €

Excluding tax
prices do not include tax. For shipment within Germany 19% MwSt will be included at checkout and in the invoice. For shipment within EU-countries you will need to provide the valid VAT number. International customers should note that all duties, import fees, and taxes are to be paid by the customer
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Combine this product with our corresponding EBV LMP2 Products: PepMix™ Peptide Pools, Dextramers®, Antigen Peptides and RepliTope™ Peptide Microarrays.

PepMix™ EBV (LMP2)

Product Code: PM-EBV-LMP2

Pool of 122 peptides derived from a peptide scan (15mers with 11 aa overlap) through Latent membrane protein 2 (LMP2) (Swiss-Prot ID: P13285) of Epstein-Barr virus (HHV4) for T cell assays.
Amount: 1 vial containing 15 nmol (appr. 25µg) per peptide
Purity: >70% (HPLC-MS)
Delivery Format: Freeze dried in amber type glass vial
Application(s): T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
Indication(s)/Topic(s): Infection, Cancer, Hodgkin's lymphoma, Burkitt's lymphoma, Nasopharyngeal carcinoma, Dermatomyositis, Systemic lupus erythematosus, Rheumatoid arthritis, Sjgren's syndrome, Multiple sclerosis
Delivery Time: 2-5 days

PepMix™ Peptide Pools
The use of complete protein-spanning mixtures of overlapping peptides (PepMix) is extremely efficient for immunostimulation of T-lymphocytes and diagnostic applications. In order to establish reliable and validated T-cell assays such as ELISPOT, appropriate positive and negative controls are essential. Selection of such controls helps to confirm proper functionality of the assay as well as viability of the cells used. In addition, high quality controls are most important to establish standardized assay protocols in clinical setups. Compared to commonly used controls like phytohemagglutinin (PHA) and concanavalin A (ConA) that stimulate T-cells as well as other cell types or full length antigens, synthetic peptide pools offer the advantage of a high batch-to-batch reproducibility, applicability of reliable chemical and biochemical QC/QA measures and shelf stability when stored as freeze dried aliquots.

Benefits of PepMix™
- Equivalent or better stimulation of CD4+ and CD8+ T-cell responses compared to whole protein antigens
- Simultaneous detection of CD4+ and CD8+ responses in a single sample
- Improved responses in stored blood and PBM cells compared to whole protein antigens

PepMix™ EBV (LMP2)

References:
Read References with PepMix™ Peptide Pools - Infectious Diseases

Application Notes
"Developing Multi-HIV Antigen Specific T-Cells as a Component of a Cure Strategy"
Lam et al. (2015) Full text
"Peptide-stimulated Expansion of Virus-specific T cells For Preventative Treatment After Allogeneic Stem Cell Transplantation"
Gary et al. (2015) Full text

Testimonials
"To establish a novel role for myeloid derived suppressor cells (Pallett et al, Nat. Med. 2015) in chronic viral infection, we utilised the PepMix CEF Pool (extended) as well as a custom synthesized PepMix spanning the core region of HBV genotype D . Whereas, the CEF peptide pool consists of 32 peptides, each corresponding to a defined HLA class I-restricted T-cell epitope from Cytomegalo, Epstein-Barr, and Influenza virus, the latter custom PepMix included 15meric peptides overlapping by 10 amino acids. Specifically this composition enabled us to monitor both the antiviral CD8+ and CD4+ T cell responses in chronic HBV infection and the non-antigen specific T cells that are known to mediate immunopathology in the liver. Our entire experience with JPT, from ordering/delivery to use in the lab was excellent. Not only were the reagents able to perform reliably and consistently in vitro from batch to batch, the customer and technical support provided was continually available and efficient when needed. JPT will remain our "go-to" company for purchasing peptides."
Dr. Laura J Pallett, Infection and Immunity, University College London, UK

PepMix™ EBV (LMP2)

 
Code
Product Name
 
Price
Buy
PM-EBV-BMLF1
PepMix™ EBV (BMLF1)
Pool of 117 peptides derived from a peptide scan through mRNA export factor EB2 (BMLF1) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-BMRF1
PepMix™ EBV (BMRF1)
Pool of 99 peptides derived from a peptide scan through DNA polymerase processivity factor BMRF1 of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-BRLF1
PepMix™ EBV (BRLF1)
Pool of 149 peptides derived from a peptide scan through Transcription activator BRLF1 of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-BZLF1
PepMix™ EBV (BZLF1)
Pool of 59 peptides derived from a peptide scan through Trans-activator protein BZLF1 of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-EBNA1
PepMix™ EBV (EBNA1)
Pool of 158 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 1 (EBNA1) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-EBNA2
PepMix™ EBV (EBNA2)
Pool of 119 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 2 (EBNA2) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-EBNA3a
PepMix™ EBV (EBNA3a)
Pool of 234 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 3 (EBNA3a) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-EBNA3b
PepMix™ EBV (EBNA3b)
Pool of 279 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 4 (EBNA3b) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-EBNA3c
PepMix™ EBV (EBNA3c)
Pool of 265 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 6 (EBNA3c) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-EBNA-LP
PepMix™ EBV (EBNA-LP)
Pool of 124 peptides derived from a peptide scan through Epstein-Barr nuclear antigen leader protein (EBNA-LP) of Epstein-Barr virus (HHV4)
add to cart
PM-EBV-GP350/GP340
PepMix™ EBV (GP350/GP340)
Pool of 224 peptides derived from a peptide scan (15mers with 11 aa overlap) through Envelope glycoprotein GP350/GP340 of Epstein-Barr virus (HHV4)
add to cart
PM-EBV-LMP1
PepMix™ EBV (LMP1)
Pool of 94 peptides derived from a peptide scan through Latent membrane protein 1 (LMP1) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
RT-EBV-BMLF1
RepliTope™ EBV (BMLF1)
Peptide microarray displaying 117 peptides derived from a peptide scan through mRNA export factor EB2 (BMLF1) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-BMRF1
RepliTope™ EBV (BMRF1)
Peptide microarray displaying 99 peptides derived from a peptide scan through DNA polymerase processivity factor BMRF1 of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-BRLF1
RepliTope™ EBV (BRLF1)
Peptide microarray displaying 149 peptides derived from a peptide scan through Transcription activator BRLF1 of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-BZLF1
RepliTope™ EBV (BZLF1)
Peptide microarray displaying 59 peptides derived from a peptide scan through Trans-activator protein BZLF1 of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-EBNA1
RepliTope™ EBV (EBNA1)
Peptide microarray displaying 158 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 1 (EBNA1) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-EBNA2
RepliTope™ EBV (EBNA2)
Peptide microarray displaying 119 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 2 (EBNA2) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-EBNA3a
RepliTope™ EBV (EBNA3a)
Peptide microarray displaying 234 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 3 (EBNA3a) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-EBNA3b
RepliTope™ EBV (EBNA3b)
Peptide microarray displaying 234 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 4 (EBNA3b) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-EBNA3c
RepliTope™ EBV (EBNA3c)
Peptide microarray displaying 265 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 6 (EBNA3c) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-EBNA-LP
RepliTope™ EBV (EBNA-LP)
Peptide microarray displaying 124 peptides derived from a peptide scan through Epstein-Barr nuclear antigen leader protein (EBNA-LP) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-GP350/GP340
RepliTope™ EBV (GP350/GP340)
Peptide microarray displaying 224 peptides derived from a peptide scan through Envelope glycoprotein GP350/GP340 of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-LMP1
RepliTope™ EBV (LMP1)
Peptide microarray displaying 94 peptides derived from a peptide scan through Latent membrane protein 1 (LMP1) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-LMP2
RepliTope™ EBV (LMP2)
Peptide microarray displaying 122 peptides derived from a peptide scan through Latent membrane protein 2 (LMP2) of Epstein-Barr virus (HHV4)
add to cart

Description

Product Code: PM-EBV-LMP2

Pool of 122 peptides derived from a peptide scan (15mers with 11 aa overlap) through Latent membrane protein 2 (LMP2) (Swiss-Prot ID: P13285) of Epstein-Barr virus (HHV4) for T cell assays.
Amount: 1 vial containing 15 nmol (appr. 25µg) per peptide
Purity: >70% (HPLC-MS)
Delivery Format: Freeze dried in amber type glass vial
Application(s): T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
Indication(s)/Topic(s): Infection, Cancer, Hodgkin's lymphoma, Burkitt's lymphoma, Nasopharyngeal carcinoma, Dermatomyositis, Systemic lupus erythematosus, Rheumatoid arthritis, Sjgren's syndrome, Multiple sclerosis
Delivery Time: 2-5 days

PepMix™ Peptide Pools
The use of complete protein-spanning mixtures of overlapping peptides (PepMix) is extremely efficient for immunostimulation of T-lymphocytes and diagnostic applications. In order to establish reliable and validated T-cell assays such as ELISPOT, appropriate positive and negative controls are essential. Selection of such controls helps to confirm proper functionality of the assay as well as viability of the cells used. In addition, high quality controls are most important to establish standardized assay protocols in clinical setups. Compared to commonly used controls like phytohemagglutinin (PHA) and concanavalin A (ConA) that stimulate T-cells as well as other cell types or full length antigens, synthetic peptide pools offer the advantage of a high batch-to-batch reproducibility, applicability of reliable chemical and biochemical QC/QA measures and shelf stability when stored as freeze dried aliquots.

Benefits of PepMix™
- Equivalent or better stimulation of CD4+ and CD8+ T-cell responses compared to whole protein antigens
- Simultaneous detection of CD4+ and CD8+ responses in a single sample
- Improved responses in stored blood and PBM cells compared to whole protein antigens

References

References:
Read References with PepMix™ Peptide Pools - Infectious Diseases

Application Notes
"Developing Multi-HIV Antigen Specific T-Cells as a Component of a Cure Strategy"
Lam et al. (2015) Full text
"Peptide-stimulated Expansion of Virus-specific T cells For Preventative Treatment After Allogeneic Stem Cell Transplantation"
Gary et al. (2015) Full text

Testimonials
"To establish a novel role for myeloid derived suppressor cells (Pallett et al, Nat. Med. 2015) in chronic viral infection, we utilised the PepMix CEF Pool (extended) as well as a custom synthesized PepMix spanning the core region of HBV genotype D . Whereas, the CEF peptide pool consists of 32 peptides, each corresponding to a defined HLA class I-restricted T-cell epitope from Cytomegalo, Epstein-Barr, and Influenza virus, the latter custom PepMix included 15meric peptides overlapping by 10 amino acids. Specifically this composition enabled us to monitor both the antiviral CD8+ and CD4+ T cell responses in chronic HBV infection and the non-antigen specific T cells that are known to mediate immunopathology in the liver. Our entire experience with JPT, from ordering/delivery to use in the lab was excellent. Not only were the reagents able to perform reliably and consistently in vitro from batch to batch, the customer and technical support provided was continually available and efficient when needed. JPT will remain our "go-to" company for purchasing peptides."
Dr. Laura J Pallett, Infection and Immunity, University College London, UK

Documentation

Properties

Related Products

PM-EBV-BMLF1
PepMix™ EBV (BMLF1)
Pool of 117 peptides derived from a peptide scan through mRNA export factor EB2 (BMLF1) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-BMRF1
PepMix™ EBV (BMRF1)
Pool of 99 peptides derived from a peptide scan through DNA polymerase processivity factor BMRF1 of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-BRLF1
PepMix™ EBV (BRLF1)
Pool of 149 peptides derived from a peptide scan through Transcription activator BRLF1 of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-BZLF1
PepMix™ EBV (BZLF1)
Pool of 59 peptides derived from a peptide scan through Trans-activator protein BZLF1 of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-EBNA1
PepMix™ EBV (EBNA1)
Pool of 158 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 1 (EBNA1) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-EBNA2
PepMix™ EBV (EBNA2)
Pool of 119 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 2 (EBNA2) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-EBNA3a
PepMix™ EBV (EBNA3a)
Pool of 234 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 3 (EBNA3a) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-EBNA3b
PepMix™ EBV (EBNA3b)
Pool of 279 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 4 (EBNA3b) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-EBNA3c
PepMix™ EBV (EBNA3c)
Pool of 265 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 6 (EBNA3c) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
PM-EBV-EBNA-LP
PepMix™ EBV (EBNA-LP)
Pool of 124 peptides derived from a peptide scan through Epstein-Barr nuclear antigen leader protein (EBNA-LP) of Epstein-Barr virus (HHV4)
add to cart
PM-EBV-GP350/GP340
PepMix™ EBV (GP350/GP340)
Pool of 224 peptides derived from a peptide scan (15mers with 11 aa overlap) through Envelope glycoprotein GP350/GP340 of Epstein-Barr virus (HHV4)
add to cart
PM-EBV-LMP1
PepMix™ EBV (LMP1)
Pool of 94 peptides derived from a peptide scan through Latent membrane protein 1 (LMP1) of Epstein-Barr virus (HHV4) for T cell assays
add to cart
RT-EBV-BMLF1
RepliTope™ EBV (BMLF1)
Peptide microarray displaying 117 peptides derived from a peptide scan through mRNA export factor EB2 (BMLF1) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-BMRF1
RepliTope™ EBV (BMRF1)
Peptide microarray displaying 99 peptides derived from a peptide scan through DNA polymerase processivity factor BMRF1 of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-BRLF1
RepliTope™ EBV (BRLF1)
Peptide microarray displaying 149 peptides derived from a peptide scan through Transcription activator BRLF1 of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-BZLF1
RepliTope™ EBV (BZLF1)
Peptide microarray displaying 59 peptides derived from a peptide scan through Trans-activator protein BZLF1 of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-EBNA1
RepliTope™ EBV (EBNA1)
Peptide microarray displaying 158 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 1 (EBNA1) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-EBNA2
RepliTope™ EBV (EBNA2)
Peptide microarray displaying 119 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 2 (EBNA2) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-EBNA3a
RepliTope™ EBV (EBNA3a)
Peptide microarray displaying 234 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 3 (EBNA3a) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-EBNA3b
RepliTope™ EBV (EBNA3b)
Peptide microarray displaying 234 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 4 (EBNA3b) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-EBNA3c
RepliTope™ EBV (EBNA3c)
Peptide microarray displaying 265 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 6 (EBNA3c) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-EBNA-LP
RepliTope™ EBV (EBNA-LP)
Peptide microarray displaying 124 peptides derived from a peptide scan through Epstein-Barr nuclear antigen leader protein (EBNA-LP) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-GP350/GP340
RepliTope™ EBV (GP350/GP340)
Peptide microarray displaying 224 peptides derived from a peptide scan through Envelope glycoprotein GP350/GP340 of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-LMP1
RepliTope™ EBV (LMP1)
Peptide microarray displaying 94 peptides derived from a peptide scan through Latent membrane protein 1 (LMP1) of Epstein-Barr virus (HHV4)
add to cart
RT-EBV-LMP2
RepliTope™ EBV (LMP2)
Peptide microarray displaying 122 peptides derived from a peptide scan through Latent membrane protein 2 (LMP2) of Epstein-Barr virus (HHV4)
add to cart

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Contact us:

JPT Peptide Technologies GmbH
Volmerstrasse 5
12489 Berlin, Germany
Technical Support:
T: +49-30-6392-7878
X: +49-30-6392-7888
e-mail: peptide@jpt.com
USA & Canada:
T: 1.888.JPT.COM0 (1.888.578.2660)
X: 1.888.JPT.COM6 (1.888.578.2666)
e-mail: peptide@jpt.com