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CATALOG PRODUCT FINDER

PepMix™ BKV (capsid protein VP2, isoform VP3)

PepMix™ BKV (capsid protein VP2, isoform VP3)
  
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Delivery in 2-5 days
317,00 €
317,00 €

Excluding tax
prices do not include tax. For shipment within Germany 19% MwSt will be included at checkout and in the invoice. For shipment within EU-countries you will need to provide the valid VAT number. International customers should note that all duties, import fees, and taxes are to be paid by the customer
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PepMix™ BKV (capsid protein VP2, isoform VP3)

Product Code: PM-BKV-VP3

Pool of 56 peptides derived from a peptide scan (15mers with 11 aa overlap) through Minor capsid protein VP2, isoform VP3 (Swiss-Prot ID: P03094) of BK polyomavirus for T cell assays.
Amount: 1 vial containing 15 nmol (appr. 25µg) per peptide
Purity: >70% (HPLC-MS)
Delivery Format: Freeze dried in amber type glass vial
Application(s): T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
Indication(s)/Topic(s): Infection, AIDS, Cancer chemotherapy, Transplantation, Merkel cell carcinoma, PML and BK nephropathy
Delivery Time: 2-5 days

PepMix™ Peptide Pools
The use of complete protein-spanning mixtures of overlapping peptides (PepMix) is extremely efficient for immunostimulation of T-lymphocytes and diagnostic applications. In order to establish reliable and validated T-cell assays such as ELISPOT, appropriate positive and negative controls are essential. Selection of such controls helps to confirm proper functionality of the assay as well as viability of the cells used. In addition, high quality controls are most important to establish standardized assay protocols in clinical setups. Compared to commonly used controls like phytohemagglutinin (PHA) and concanavalin A (ConA) that stimulate T-cells as well as other cell types or full length antigens, synthetic peptide pools offer the advantage of a high batch-to-batch reproducibility, applicability of reliable chemical and biochemical QC/QA measures and shelf stability when stored as freeze dried aliquots.

Benefits of PepMix™
- Equivalent or better stimulation of CD4+ and CD8+ T-cell responses compared to whole protein antigens
- Simultaneous detection of CD4+ and CD8+ responses in a single sample
- Improved responses in stored blood and PBM cells compared to whole protein antigens

PepMix™ BKV (capsid protein VP2, isoform VP3)

References:
Read References with PepMix™ Peptide Pools - Infectious Diseases

Application Notes
"Developing Multi-HIV Antigen Specific T-Cells as a Component of a Cure Strategy"
Lam et al. (2015) Full text
"Peptide-stimulated Expansion of Virus-specific T cells For Preventative Treatment After Allogeneic Stem Cell Transplantation"
Gary et al. (2015) Full text

Testimonials
"To establish a novel role for myeloid derived suppressor cells (Pallett et al, Nat. Med. 2015) in chronic viral infection, we utilised the PepMix CEF Pool (extended) as well as a custom synthesized PepMix spanning the core region of HBV genotype D . Whereas, the CEF peptide pool consists of 32 peptides, each corresponding to a defined HLA class I-restricted T-cell epitope from Cytomegalo, Epstein-Barr, and Influenza virus, the latter custom PepMix included 15meric peptides overlapping by 10 amino acids. Specifically this composition enabled us to monitor both the antiviral CD8+ and CD4+ T cell responses in chronic HBV infection and the non-antigen specific T cells that are known to mediate immunopathology in the liver. Our entire experience with JPT, from ordering/delivery to use in the lab was excellent. Not only were the reagents able to perform reliably and consistently in vitro from batch to batch, the customer and technical support provided was continually available and efficient when needed. JPT will remain our "go-to" company for purchasing peptides."
Dr. Laura J Pallett, Infection and Immunity, University College London, UK

PepMix™ BKV (capsid protein VP2, isoform VP3)

 
Code
Product Name
 
Price
Buy
PM-BKV-VP1
PepMix™ BKV (capsid protein VP1)
Pool of 88 peptides derived from a peptide scan through Major capsid protein VP1 of BK polyomavirus for T cell assays (e.g. ELISPOT)
add to cart
PM-BKV-VP2
PepMix™ BKV (capsid protein VP2)
Pool of 85 peptides derived from a peptide scan through Minor capsid protein VP2 of BK polyomavirus for T cell assays (e.g. ELISPOT)
add to cart
PM-BKV-LTA
PepMix™ BKV (large T antigen)
Pool of 170 peptides derived from a peptide scan through Large T antigen of BK polyomavirus for T cell assays (antigen specific T-cell stimulation)
add to cart
PM-BKV-STA
PepMix™ BKV (small T antigen)
Pool of 41 peptides derived from a peptide scan through Small t antigen of BK polyomavirus for T cell assays (e.g. antigen specific T-cell stimulation)
add to cart
RT-BKV-VP2
RepliTope™ BKV (capsid protein VP2)
Peptide microarray displaying 85 peptides derived from a peptide scan through Minor capsid protein VP2 of BK polyomavirus
add to cart
RT-BKV-VP3
RepliTope™ BKV (capsid protein VP2, isoform VP3)
Peptide microarray displaying 56 peptides derived from a peptide scan through Minor capsid protein VP2, isoform VP3 of BK polyomavirus
add to cart
RT-0004
RepliTope™ BKV (coat protein VP1)
Peptide microarray displaying 88 peptides derived from a peptide scan through Major capsid protein VP1 of BK polyomavirus
add to cart
RT-0005
RepliTope™ BKV (large T antigen)
Peptide microarray displaying 170 peptides derived from a peptide scan through Large T antigen of BK polyomavirus
add to cart
RT-BKV-STA
RepliTope™ BKV (small T antigen)
Peptide microarray displaying 41 peptides derived from a peptide scan through Small t antigen of BK polyomavirus
add to cart

Description

Product Code: PM-BKV-VP3

Pool of 56 peptides derived from a peptide scan (15mers with 11 aa overlap) through Minor capsid protein VP2, isoform VP3 (Swiss-Prot ID: P03094) of BK polyomavirus for T cell assays.
Amount: 1 vial containing 15 nmol (appr. 25µg) per peptide
Purity: >70% (HPLC-MS)
Delivery Format: Freeze dried in amber type glass vial
Application(s): T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
Indication(s)/Topic(s): Infection, AIDS, Cancer chemotherapy, Transplantation, Merkel cell carcinoma, PML and BK nephropathy
Delivery Time: 2-5 days

PepMix™ Peptide Pools
The use of complete protein-spanning mixtures of overlapping peptides (PepMix) is extremely efficient for immunostimulation of T-lymphocytes and diagnostic applications. In order to establish reliable and validated T-cell assays such as ELISPOT, appropriate positive and negative controls are essential. Selection of such controls helps to confirm proper functionality of the assay as well as viability of the cells used. In addition, high quality controls are most important to establish standardized assay protocols in clinical setups. Compared to commonly used controls like phytohemagglutinin (PHA) and concanavalin A (ConA) that stimulate T-cells as well as other cell types or full length antigens, synthetic peptide pools offer the advantage of a high batch-to-batch reproducibility, applicability of reliable chemical and biochemical QC/QA measures and shelf stability when stored as freeze dried aliquots.

Benefits of PepMix™
- Equivalent or better stimulation of CD4+ and CD8+ T-cell responses compared to whole protein antigens
- Simultaneous detection of CD4+ and CD8+ responses in a single sample
- Improved responses in stored blood and PBM cells compared to whole protein antigens

References

References:
Read References with PepMix™ Peptide Pools - Infectious Diseases

Application Notes
"Developing Multi-HIV Antigen Specific T-Cells as a Component of a Cure Strategy"
Lam et al. (2015) Full text
"Peptide-stimulated Expansion of Virus-specific T cells For Preventative Treatment After Allogeneic Stem Cell Transplantation"
Gary et al. (2015) Full text

Testimonials
"To establish a novel role for myeloid derived suppressor cells (Pallett et al, Nat. Med. 2015) in chronic viral infection, we utilised the PepMix CEF Pool (extended) as well as a custom synthesized PepMix spanning the core region of HBV genotype D . Whereas, the CEF peptide pool consists of 32 peptides, each corresponding to a defined HLA class I-restricted T-cell epitope from Cytomegalo, Epstein-Barr, and Influenza virus, the latter custom PepMix included 15meric peptides overlapping by 10 amino acids. Specifically this composition enabled us to monitor both the antiviral CD8+ and CD4+ T cell responses in chronic HBV infection and the non-antigen specific T cells that are known to mediate immunopathology in the liver. Our entire experience with JPT, from ordering/delivery to use in the lab was excellent. Not only were the reagents able to perform reliably and consistently in vitro from batch to batch, the customer and technical support provided was continually available and efficient when needed. JPT will remain our "go-to" company for purchasing peptides."
Dr. Laura J Pallett, Infection and Immunity, University College London, UK

Documentation

Properties

Related Products

PM-BKV-VP1
PepMix™ BKV (capsid protein VP1)
Pool of 88 peptides derived from a peptide scan through Major capsid protein VP1 of BK polyomavirus for T cell assays (e.g. ELISPOT)
add to cart
PM-BKV-VP2
PepMix™ BKV (capsid protein VP2)
Pool of 85 peptides derived from a peptide scan through Minor capsid protein VP2 of BK polyomavirus for T cell assays (e.g. ELISPOT)
add to cart
PM-BKV-LTA
PepMix™ BKV (large T antigen)
Pool of 170 peptides derived from a peptide scan through Large T antigen of BK polyomavirus for T cell assays (antigen specific T-cell stimulation)
add to cart
PM-BKV-STA
PepMix™ BKV (small T antigen)
Pool of 41 peptides derived from a peptide scan through Small t antigen of BK polyomavirus for T cell assays (e.g. antigen specific T-cell stimulation)
add to cart
RT-BKV-VP2
RepliTope™ BKV (capsid protein VP2)
Peptide microarray displaying 85 peptides derived from a peptide scan through Minor capsid protein VP2 of BK polyomavirus
add to cart
RT-BKV-VP3
RepliTope™ BKV (capsid protein VP2, isoform VP3)
Peptide microarray displaying 56 peptides derived from a peptide scan through Minor capsid protein VP2, isoform VP3 of BK polyomavirus
add to cart
RT-0004
RepliTope™ BKV (coat protein VP1)
Peptide microarray displaying 88 peptides derived from a peptide scan through Major capsid protein VP1 of BK polyomavirus
add to cart
RT-0005
RepliTope™ BKV (large T antigen)
Peptide microarray displaying 170 peptides derived from a peptide scan through Large T antigen of BK polyomavirus
add to cart
RT-BKV-STA
RepliTope™ BKV (small T antigen)
Peptide microarray displaying 41 peptides derived from a peptide scan through Small t antigen of BK polyomavirus
add to cart

Quality Assurance

All production is performed according to ISO 9001:2015 standards.

ISO 9001

 
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Contact us:

JPT Peptide Technologies GmbH
Volmerstrasse 5
12489 Berlin, Germany
Technical Support:
T: +49-30-6392-7878
X: +49-30-6392-7888
e-mail: peptide@jpt.com
USA & Canada:
T: 1.888.JPT.COM0 (1.888.578.2660)
X: 1.888.JPT.COM6 (1.888.578.2666)
e-mail: peptide@jpt.com