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Acetylome - Acetyltransferase Microarray

Acetylome - Acetyltransferase Microarray
  
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Delivery in 10-12 days
167,75 €
167,75 €

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Acetylome - Acetyltransferase Microarray

Product Code: AT-MA_02

Peptide microarraydisplaying 5599 peptides derived from reported human acetylation sites (plus 384 control peptides). All 5599 peptides carryunmodified lysine residues. Readout is performed by differential measurement, allowing comparative analysis in absence (control) and presence of acetylase (or other) activities. A control microarray is provided with each order.
Amount:
1 peptide microarray (each peptide is deposited 1x per subarray, 3 subarrays per slide) + 1 control microarray per order +dummy slides and spacers (needed for manual incubation)
Purity: Free of truncated sequences
Delivery Format: Peptides immobilized onto glass slide (3 x 1 inches; 75 by 25 mm)
Application(s): Binding experiments, Substrate identification, Acetyltransferase assays, Acetyltransferase inhibitor screens
Indication(s)/Topic(s): Cancer, Acetyltransferase, Histones, Gene regulation and expression, Epigenetics, Cell signaling, Acetylome, Deacetylase, Methyltransferase
Delivery Time: 2-5 days

Acetyltransferase & Deacetylase Microarrays
JPT Peptide Technologies applies its unique peptide microarray platform to generate peptide microarrays on glass slides for characterization of enzymes such as acetyltransferases, methyltransferases and deacetylases. Peptides are immobilized on glass slides via a flexible linker. Chemoselective coupling generates microarrays displaying covalently attached peptides. Multiple identical copies of each microarray are produced. Incubation can be performed manually or automated. Read-out via fluorescence results in low background and high sensitivity.

Benefits of JPT's Acetyltransferase & Deacetylase Microarrays
- Unique collection of all identified human acetylation sites
- Get hundreds of identical microarray copies
- Peptides are free of truncated sequences
- Small amounts of your precious samples are needed for incubation
- Applicable to a variety of biological samples (e.g. serum, lysate, phosphatase)
- Low background on glass surface. Read-out via fluorescence
- Save time for HTS assay setup
- Screen thousands of potential peptide substrates economically

Acetylome - Acetyltransferase Microarray

References:
Read References with Enzyme Substrate Microarrays

Application Notes for Enzyme Substrate Microarrays
"Exploring the human acetylome using high-density peptide microarrays"
Masch et al., Application Note (2012) (full text)
"Unraveling Phosphorylation of the Splicing Factor SC35 by the Dual Signaling Kinase PKC in Human T-Cells"
Rao et al., Application Note (2016) (full text)
"Use of High-Density Histone Peptide Arrays for Parsing the Specificity of a Histone Modifying Enzyme Complex"
Wilczek et al., Application Note (2013) (full text)

Testimonial
"We have successfully applied JPT's peptide microarrays as a screening tool for potential kinases transfering phosphate to phosphorylation sites identified by mass spectrometry. The triplicate alignment as well as the thorough selection of controls enabled generation of high quality data confirming our in vivo data generated by means of affinity chromatographic procedures."
Marcelo P. Coba, PhD, The Wellcome Trust Sanger Institute, Cambridge, UK

Acetylome - Acetyltransferase Microarray

 
Code
Product Name
 
Price
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KIN-MA-PhK
Annotated Phosphosites-Kinase
Collection of 720 annotated human phosphorylation site derived peptides
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His_MA_01
Histone Code Peptide Microarrays
Extensive peptide library covering all known natural variants of histone sequences and modfications displayed on one microarray (> 3800 peptides)
add to cart
AT-MA_01
Acetylome - Deacetylase Microarray
Peptide microarray displaying 5599 peptides derived from reported human acetylation sites (plus 384 control peptides)
add to cart

Description

Product Code: AT-MA_02

Peptide microarraydisplaying 5599 peptides derived from reported human acetylation sites (plus 384 control peptides). All 5599 peptides carryunmodified lysine residues. Readout is performed by differential measurement, allowing comparative analysis in absence (control) and presence of acetylase (or other) activities. A control microarray is provided with each order.
Amount:
1 peptide microarray (each peptide is deposited 1x per subarray, 3 subarrays per slide) + 1 control microarray per order +dummy slides and spacers (needed for manual incubation)
Purity: Free of truncated sequences
Delivery Format: Peptides immobilized onto glass slide (3 x 1 inches; 75 by 25 mm)
Application(s): Binding experiments, Substrate identification, Acetyltransferase assays, Acetyltransferase inhibitor screens
Indication(s)/Topic(s): Cancer, Acetyltransferase, Histones, Gene regulation and expression, Epigenetics, Cell signaling, Acetylome, Deacetylase, Methyltransferase
Delivery Time: 2-5 days

Acetyltransferase & Deacetylase Microarrays
JPT Peptide Technologies applies its unique peptide microarray platform to generate peptide microarrays on glass slides for characterization of enzymes such as acetyltransferases, methyltransferases and deacetylases. Peptides are immobilized on glass slides via a flexible linker. Chemoselective coupling generates microarrays displaying covalently attached peptides. Multiple identical copies of each microarray are produced. Incubation can be performed manually or automated. Read-out via fluorescence results in low background and high sensitivity.

Benefits of JPT's Acetyltransferase & Deacetylase Microarrays
- Unique collection of all identified human acetylation sites
- Get hundreds of identical microarray copies
- Peptides are free of truncated sequences
- Small amounts of your precious samples are needed for incubation
- Applicable to a variety of biological samples (e.g. serum, lysate, phosphatase)
- Low background on glass surface. Read-out via fluorescence
- Save time for HTS assay setup
- Screen thousands of potential peptide substrates economically

References

References:
Read References with Enzyme Substrate Microarrays

Application Notes for Enzyme Substrate Microarrays
"Exploring the human acetylome using high-density peptide microarrays"
Masch et al., Application Note (2012) (full text)
"Unraveling Phosphorylation of the Splicing Factor SC35 by the Dual Signaling Kinase PKC in Human T-Cells"
Rao et al., Application Note (2016) (full text)
"Use of High-Density Histone Peptide Arrays for Parsing the Specificity of a Histone Modifying Enzyme Complex"
Wilczek et al., Application Note (2013) (full text)

Testimonial
"We have successfully applied JPT's peptide microarrays as a screening tool for potential kinases transfering phosphate to phosphorylation sites identified by mass spectrometry. The triplicate alignment as well as the thorough selection of controls enabled generation of high quality data confirming our in vivo data generated by means of affinity chromatographic procedures."
Marcelo P. Coba, PhD, The Wellcome Trust Sanger Institute, Cambridge, UK

Documentation

Properties

Related Products

KIN-MA-PhK
Annotated Phosphosites-Kinase
Collection of 720 annotated human phosphorylation site derived peptides
add to cart
His_MA_01
Histone Code Peptide Microarrays
Extensive peptide library covering all known natural variants of histone sequences and modfications displayed on one microarray (> 3800 peptides)
add to cart
AT-MA_01
Acetylome - Deacetylase Microarray
Peptide microarray displaying 5599 peptides derived from reported human acetylation sites (plus 384 control peptides)
add to cart

Quality Assurance

All production is performed according to ISO 9001:2015 standards.

ISO 9001

 
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Contact us:

JPT Peptide Technologies GmbH
Volmerstrasse 5
12489 Berlin, Germany
Technical Support:
T: +49-30-6392-7878
X: +49-30-6392-7888
e-mail: peptide@jpt.com
USA & Canada:
T: 1.888.JPT.COM0 (1.888.578.2660)
X: 1.888.JPT.COM6 (1.888.578.2666)
e-mail: peptide@jpt.com