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MHC I Dextramer H-2 Dk (RRLGRTLLL)

MHC I Dextramer H-2 Dk (RRLGRTLLL)

  
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Delivery in 10-12 days
1.149,00 €
1.149,00 €

Excluding tax
prices do not include tax. For shipment within Germany 19% MwSt will be included at checkout and in the invoice. For shipment within EU-countries you will need to provide the valid VAT number. International customers should note that all duties, import fees, and taxes are to be paid by the customer
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MHC I Dextramer H-2 Dk (RRLGRTLLL)

Product Code: MHC2636

Fluorescent MHC Dextramers® for sensitive and specific detection of antigen-specific T cells using flow cytometry. Available in three colors (PE, APC, and FITC), covering human, mouse and monkey alleles.
Amount: 1 vial containing 50 /150 / 500 or 1000 tests
Application(s): Cellular immune response, Immune monitoring, T-cell assays, Immunohistochemistry
Indication(s)/Topic(s): AIDS, Autoimmune disease, Breast cancer, Cancer, Cancer chemotherapy, Control, Diabetes, Graft-vs-host disease, Hematopoetic system, Hepatitis, Infection, Malaria, Malignant genital cancers, Melanoma, Prostate cancer, Testis/ovary cancer, Tuberculosis, Transplantation, Vaccination, Wilms tumor 1
Delivery Time: 10-12 days

MHC I Dextramers®
MHC Multimers such as Dextramers® are used for detection, enumeration and isolation of antigen-specific T cells in fluid cell samples (PBMC, blood) by flow cytometry, and can be applied to tissue sections to visualize antigen-specific T cells in situ.Fields of application are vaccine and immunotherapeutic development, clinical trials, immune monitoring of transplantation patients, patients with HIV and many more. The MHC class I Dextramers® combine a dextran polymer backbone with a high number of MHC and fluorochrome molecules. This enhances their staining intensity, thereby increasing resolution and the signal-to-noise ratio with minimal background staining. In addition, the polymer backbone stabilizes the MHC-peptide complexes and fluorochromes.

Benefits of MHC I Dextramers®
- More MHC molecules and more fluorochromes than conventional MHC multimers (e.g. tetramers)
- Higher sensitivity (important for low affinity epitopes as commonly found in cancer & autoimmune disease)
- Very stable
- Custom-made Dextramers® available upon request

MHC I Dextramer H-2 Dk (RRLGRTLLL)

References:
Read References with MHC Multimers

MHC I Dextramer H-2 Dk (RRLGRTLLL)

 
Code
Product Name
 
Price
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PM-NYE
PepMix™ Human (NY-ESO-1)
Pool of 43 peptides derived from a peptide scan through Cancer/testis antigen 1 (NY-ESO-1) of Homo sapiens for T cell assays (e.g. ELISPOT)
add to cart
RX01
Melanoma Dextramer Collection 1
Multimer collection of 6 carefully selected melanoma specific antigen Dextramers and one control. Two aliquots / antigen with different fluorescent labels (PE and APC) are deli...
add to cart
RX03-APC
Virus Dextramer Collection 1-APC
Multimer collection of 4 selected virus (CMV, EBV, BKV & Influenza) antigen Dextramers and one control. The set comes with APC label
add to cart

Description

Product Code: MHC2636

Fluorescent MHC Dextramers® for sensitive and specific detection of antigen-specific T cells using flow cytometry. Available in three colors (PE, APC, and FITC), covering human, mouse and monkey alleles.
Amount: 1 vial containing 50 /150 / 500 or 1000 tests
Application(s): Cellular immune response, Immune monitoring, T-cell assays, Immunohistochemistry
Indication(s)/Topic(s): AIDS, Autoimmune disease, Breast cancer, Cancer, Cancer chemotherapy, Control, Diabetes, Graft-vs-host disease, Hematopoetic system, Hepatitis, Infection, Malaria, Malignant genital cancers, Melanoma, Prostate cancer, Testis/ovary cancer, Tuberculosis, Transplantation, Vaccination, Wilms tumor 1
Delivery Time: 10-12 days

MHC I Dextramers®
MHC Multimers such as Dextramers® are used for detection, enumeration and isolation of antigen-specific T cells in fluid cell samples (PBMC, blood) by flow cytometry, and can be applied to tissue sections to visualize antigen-specific T cells in situ.Fields of application are vaccine and immunotherapeutic development, clinical trials, immune monitoring of transplantation patients, patients with HIV and many more. The MHC class I Dextramers® combine a dextran polymer backbone with a high number of MHC and fluorochrome molecules. This enhances their staining intensity, thereby increasing resolution and the signal-to-noise ratio with minimal background staining. In addition, the polymer backbone stabilizes the MHC-peptide complexes and fluorochromes.

Benefits of MHC I Dextramers®
- More MHC molecules and more fluorochromes than conventional MHC multimers (e.g. tetramers)
- Higher sensitivity (important for low affinity epitopes as commonly found in cancer & autoimmune disease)
- Very stable
- Custom-made Dextramers® available upon request

References

References:
Read References with MHC Multimers

Properties

Related Products

PM-NYE
PepMix™ Human (NY-ESO-1)
Pool of 43 peptides derived from a peptide scan through Cancer/testis antigen 1 (NY-ESO-1) of Homo sapiens for T cell assays (e.g. ELISPOT)
add to cart
RX01
Melanoma Dextramer Collection 1
Multimer collection of 6 carefully selected melanoma specific antigen Dextramers and one control. Two aliquots / antigen with different fluorescent labels (PE and APC) are deli...
add to cart
RX03-APC
Virus Dextramer Collection 1-APC
Multimer collection of 4 selected virus (CMV, EBV, BKV & Influenza) antigen Dextramers and one control. The set comes with APC label
add to cart

Quality Assurance

All production is performed according to ISO 9001:2015 standards.

ISO 9001

 
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JPT Peptide Technologies GmbH
Volmerstrasse 5
12489 Berlin, Germany
Technical Support:
T: +49-30-6392-7878
X: +49-30-6392-7888
e-mail: peptide@jpt.com
USA & Canada:
T: 1.888.JPT.COM0 (1.888.578.2660)
X: 1.888.JPT.COM6 (1.888.578.2666)
e-mail: peptide@jpt.com