PepMix™ Peptide Pools Pools of overlapping peptides from antigenic proteins for T-cell stimulation, T-cell expansion in T-cell assays such as ELISPOT, ICS or Flow Cytometry, e.g. for immune monitoring.
Transduction Enhancer Protransduzin™ the highly efficient transduction enhancer increases viral gene transfer in pre-clinical and clinical applications, such as ex vivo gene therapy and CAR-T cell development.
Antigen Peptides Antigen peptides represent specific epitopes for stimulation of T cells in T cell assays such as ELISPOT. We offer the corresponding MHC multimer for each antigen peptide. Antigens from different pathogens are available as well as tumor associated antigens.
Proteomics Peptides & Kits Peptide sets and pools, as well as assay standardization kits are available with stable isotope labeled or unlabeled proteotypic peptides for mass-spectrometry based proteomics such as MRM assays.
Chelate Peptides (DOTA) DOTA is linked to molecules that have affinity for various structures (e.g. somatostatin receptors in neuroendocrine tumors). The resulting compounds can be bound to radionuclided and are used with a number of radioisotopes in cancer therapy and diagnosis
Cosmetic Peptides Cosmetic Peptides such as Lysine and Cysteine Peptide are used for DPRA (Direct Peptide Reactivity Assay) for Skin Sensitization Testing. The DPRA measures the reaction of a chemical with synthetic peptides containing Cysteine (Ac‑RFAACAA‑COOH) or Lysine (Ac‑RFAAKAA‑COOH) to assess its sensitization potency. For research use only!
Immunology Standards & Controls Standards and controls for reproducible T-cell assays such as ELISPOT and multimer assays. We offer a large variety of positive and negative control peptide pools for antigen specific T cell stimulation as well as kit to produce TCR-engineered reference samples for performance control.
MHC-Multimers for reproducible detection, enumeration and isolation of antigen-specific T cells with disease specific peptides. JPT’s MHC-Multimers are Dextramers® that show a stronger staining intensity, high resolution and good signal-to-noise ratio. MHC Dextramers detect the presence of antigen-specific T cells whereas interferon-gamma-releasing assays such as ELISPOT detect the functionality of the antigen-specific T cells. A combination of the MHC Dextramer assay and a functional assay, using PepMix™ Peptide Pools is a strong tool for reliable and robust immune monitoring!
MHC Multimer Collections
Carefully selected sets of multimers for enumeration of antigen-specific CD8+ T cells with different fluorochromes available.
Individual MHC II Multimers
Fluorescent MHC II multimers available with three different fluorochromes and many alleles.
Individual MHC I Multimers
Fluorescent MHC I multimers, available in three colors, covering human, mouse and monkey alleles.