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SpikeTides™ Set Metabolic Enzymes (Human) - heavy - quantified - 1000pmol

SpikeTides™ Set Metabolic Enzymes (Human) - heavy - quantified - 1000pmol

SpikeTides™ Set Metabolic Enzymes (Human) - heavy - quantified - 1000pmol
  
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2.975,00 €
2.975,00 €

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SpikeTides™ Set Metabolic Enzymes (Human) - heavy - quantified - 1000pmol

Product Code: SPT-ME-TQL-hum-1000pm

Collection of 51 stable isotope-labeled and absolutely quantified proteotypic peptides for 24 enzymes critically involved in the human central energy metabolism for direct usage in mass-spectrometry based proteomics (MRM).
Amount: Micronic rack with 51 individual peptides (1000 pmol per peptide)
Delivery Format: Micronic tube rack
Application(s): Cancer biomarker research, MRM assays, Proteomics, SRM assays, Mass spectrometry
Indication(s)/Topic(s): Cancer, Breast cancer, Burkitt's lymphoma, Gastric cancer, Testis/ovary cancer, Cancer chemotherapy, Melanoma, Prostate cancer
Delivery Time: 2-5 days

JPT's heavy labeled and quantified SpikeTides™ Sets
JPT produced a set of proteotypic peptides for the detection of the most relevant tumor associated antigens (TAA) by mass-spectrometry based proteomics. 75 TAAs were selected and prioritized in a NCI pilot project to rank the most relevant cancer antigens to date (Cheever et al., 2009). For 61 of these TAAs JPT'synthesized proteotypic peptides with well documented MRM transition data available (www.srmatlas.org, ISB) resulting in a set of 252 proteotypic peptides for important tumor associated antigens. This set is available with light or isotopically labeled (C-terminal Arg U-13C6;U-15N4 or Lys U-13C6;U-15N2) peptides and is delivered in three 96 well plates.

Benefits of JPT's heavy labeled & quantified SpikeTides™ Sets
- Absolute quantification of multiple proteins from a single sample
- First economic absolutely quantified peptide set available
- Multiplexed analysis of disease status and therapeutic success
- MRM transitions included

SpikeTides™ Set Metabolic Enzymes (Human) - heavy - quantified - 1000pmol

References:
Read References with Absolute Quantified Peptides - SpikeTides™ TQL & SpikeTides™ TQL PLUS

Application Note
"Absolute Quantification of Metabolic Enzymes via Targeted Proteomics using a new Kit of SpikeTides™ Peptides"
Bindel et al., Application Note (2015) Full text

Testimonials
"My unit at the Banting and Best Department of Medical Research, University of Toronto Centre for Cellular and Biomolecular Research (CCBR) works on the systematic identification and quantification of proteins and protein complexes on a global level. In addition we have started to perform targeted proteomics to study protein regulation within pathways, e.g. signaling pathways during stem cell fate decision. For this we used JPT's various SpikeTides™ peptide products to build LC-MRM assays in a fast and cost efficient manner. More recently we also found new ways of using low cost SpikeTides™_TQL as quantitative peptide standards in order to quantify protein targets more accurately. We are currently in the process of validating this technology for the accurate quantification of various predicted microRNA targets."
Prof. Andrew Emili, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto

"My group studies the proteomic composition of distinct chromatin domains, the mechanisms that operate to maintain the composition of histone modifications and the associated proteins. For precise and accurate identification and quantification of histone peptides that carry multiple post-translational modifications directly from biological samples JPT's SpikeTides™ _TQL peptide standards proved to be of excellent value for our research in various projects."
Prof. Dr. Axel Imhof, Adolf-Butenandt Institute, University of Munich, Germany

Description

Product Code: SPT-ME-TQL-hum-1000pm

Collection of 51 stable isotope-labeled and absolutely quantified proteotypic peptides for 24 enzymes critically involved in the human central energy metabolism for direct usage in mass-spectrometry based proteomics (MRM).
Amount: Micronic rack with 51 individual peptides (1000 pmol per peptide)
Delivery Format: Micronic tube rack
Application(s): Cancer biomarker research, MRM assays, Proteomics, SRM assays, Mass spectrometry
Indication(s)/Topic(s): Cancer, Breast cancer, Burkitt's lymphoma, Gastric cancer, Testis/ovary cancer, Cancer chemotherapy, Melanoma, Prostate cancer
Delivery Time: 2-5 days

JPT's heavy labeled and quantified SpikeTides™ Sets
JPT produced a set of proteotypic peptides for the detection of the most relevant tumor associated antigens (TAA) by mass-spectrometry based proteomics. 75 TAAs were selected and prioritized in a NCI pilot project to rank the most relevant cancer antigens to date (Cheever et al., 2009). For 61 of these TAAs JPT'synthesized proteotypic peptides with well documented MRM transition data available (www.srmatlas.org, ISB) resulting in a set of 252 proteotypic peptides for important tumor associated antigens. This set is available with light or isotopically labeled (C-terminal Arg U-13C6;U-15N4 or Lys U-13C6;U-15N2) peptides and is delivered in three 96 well plates.

Benefits of JPT's heavy labeled & quantified SpikeTides™ Sets
- Absolute quantification of multiple proteins from a single sample
- First economic absolutely quantified peptide set available
- Multiplexed analysis of disease status and therapeutic success
- MRM transitions included

References

References:
Read References with Absolute Quantified Peptides - SpikeTides™ TQL & SpikeTides™ TQL PLUS

Application Note
"Absolute Quantification of Metabolic Enzymes via Targeted Proteomics using a new Kit of SpikeTides™ Peptides"
Bindel et al., Application Note (2015) Full text

Testimonials
"My unit at the Banting and Best Department of Medical Research, University of Toronto Centre for Cellular and Biomolecular Research (CCBR) works on the systematic identification and quantification of proteins and protein complexes on a global level. In addition we have started to perform targeted proteomics to study protein regulation within pathways, e.g. signaling pathways during stem cell fate decision. For this we used JPT's various SpikeTides™ peptide products to build LC-MRM assays in a fast and cost efficient manner. More recently we also found new ways of using low cost SpikeTides™_TQL as quantitative peptide standards in order to quantify protein targets more accurately. We are currently in the process of validating this technology for the accurate quantification of various predicted microRNA targets."
Prof. Andrew Emili, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto

"My group studies the proteomic composition of distinct chromatin domains, the mechanisms that operate to maintain the composition of histone modifications and the associated proteins. For precise and accurate identification and quantification of histone peptides that carry multiple post-translational modifications directly from biological samples JPT's SpikeTides™ _TQL peptide standards proved to be of excellent value for our research in various projects."
Prof. Dr. Axel Imhof, Adolf-Butenandt Institute, University of Munich, Germany

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Quality Assurance

All production is performed according to ISO 9001:2015 standards.

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JPT Peptide Technologies GmbH
Volmerstrasse 5
12489 Berlin, Germany
Technical Support:
T: +49-30-6392-7878
X: +49-30-6392-7888
e-mail: peptide@jpt.com
USA & Canada:
T: 1.888.JPT.COM0 (1.888.578.2660)
X: 1.888.JPT.COM6 (1.888.578.2666)
e-mail: peptide@jpt.com